{"id":9475,"date":"2022-06-05T02:00:06","date_gmt":"2022-06-05T00:00:06","guid":{"rendered":"https:\/\/voxvigor.se\/?p=9475"},"modified":"2022-06-05T02:00:06","modified_gmt":"2022-06-05T00:00:06","slug":"sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom","status":"publish","type":"post","link":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/","title":{"rendered":"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom"},"content":{"rendered":"\n

Sex faktorer kan hj\u00e4lpa till att avg\u00f6ra hur mycket litium som beh\u00f6vs f\u00f6r att behandla patienter med bipol\u00e4r sjukdom. Det visar en studie ledd av forskare vid Karolinska Institutet. Studien, som \u00e4r publicerad i tidskriften\u00a0The Lancet Psychiatry<\/em>, pekar ocks\u00e5 ut genetiska mark\u00f6rer som tycks p\u00e5verka hur snabbt kroppen g\u00f6r sig av med litium.<\/strong><\/h3>\n\n\n\n


\u2013 V\u00e5r modell \u00e4r redan nu anv\u00e4ndbar f\u00f6r att f\u00f6ruts\u00e4ga hur mycket litium en patient med bipol\u00e4r sjukdom kommer att beh\u00f6va. Detta kan minska tid spenderad p\u00e5 att hitta r\u00e4tt dos f\u00f6r varje patient, vilket kan ha livsavg\u00f6rande betydelse. Det s\u00e4ger Martin Schalling, professor vid institutionen f\u00f6r molekyl\u00e4r medicin och kirurgi, Karolinska Institutet, och studiens sistef\u00f6rfattare.<\/p>\n\n\n\n

\"\"
Martin Schalling – Professor – Institutionen
f\u00f6r Molekyl\u00e4r Medicin och Kirurgi (MMK)
Fotograf: Ulf Sirborn<\/figcaption><\/figure>\n\n\n\n

Litium \u00e4r en av de viktigaste behandlingarna f\u00f6r patienter med bipol\u00e4r sjukdom, ett tillst\u00e5nd som \u00e4r kopplat till \u00f6kad risk f\u00f6r sj\u00e4lvmord. Den kemiska substansen fungerar som en hum\u00f6rstabiliserare och minskar episoder av depression och mani. Hur stort behovet \u00e4r varierar stort mellan individer. Att hitta r\u00e4tt dos f\u00f6r varje patient \u00e4r avg\u00f6rande. F\u00f6r mycket kan vara giftigt medan f\u00f6r lite inte ger n\u00e5gon effekt. L\u00e4kare brukar starta behandlingen med l\u00e5ga doser som \u00f6kar \u00f6ver tiden f\u00f6r att minska risken f\u00f6r biverkningar. Det inneb\u00e4r att det kan ta m\u00e5nader innan l\u00e4kemedlet har n\u00e5gon verkan.<\/p>\n\n\n\n

Ny typ av studie med m\u00e5nga deltagare<\/h4>\n\n\n\n

F\u00f6r att \u00f6vervinna dessa utmaningar har forskare l\u00e4nge f\u00f6rs\u00f6kt att hitta en modell som kan f\u00f6ruts\u00e4ga dosresponsen, hur kroppen svarar, hos individuella patienter. Tidigare studier har identifierat mark\u00f6rer som \u00e5lder, k\u00f6n och njurfunktion som m\u00f6jliga f\u00f6ruts\u00e4gelser f\u00f6r hur snabbt kroppen uts\u00f6ndrar litium. Det \u00e4r anv\u00e4ndbart f\u00f6r att ber\u00e4kna hur stort behovet \u00e4r varje dag. De flesta studier har dock varit begr\u00e4nsade till relativt f\u00e5 deltagare.<\/p>\n\n\n\n

I den aktuella studien har forskarna unders\u00f6kt elektroniska patientjournaler och registerdata fr\u00e5n totalt 2,357 patienter med bipol\u00e4r sjukdom. Det \u00e4r det st\u00f6rsta antalet deltagare f\u00f6r den h\u00e4r typen av studie hittills. B\u00e5de m\u00e4n och kvinnor fr\u00e5n 17 till 89 \u00e5rs \u00e5lder, mestadels av europeisk h\u00e4rkomst, ingick i studien.<\/p>\n\n\n\n

Studien hittade samband mellan uts\u00f6ndring av litium och \u00e5lder, k\u00f6n, njurfunktion (m\u00e4tt som eGFR), serum litiumkoncentration och medicinering med urindrivande l\u00e4kemedel och substanser riktade mot renin-angiotensin-aldosteronsystemet\u00a0(RAAS), vilket \u00e4r anv\u00e4ndbart vid bland annat h\u00f6gt blodtryck.<\/p>\n\n\n\n

Vissa grupper beh\u00f6ver mindre litium<\/h4>\n\n\n\n

\u2013 V\u00e5ra fynd tyder p\u00e5 att \u00e4ldre personer, kvinnor, patienter med nedsatt njurfunktion och individer som tar vissa mediciner beh\u00f6ver l\u00e4gre doser av litium. Intressant nog uppt\u00e4ckte vi ocks\u00e5 att m\u00e4ngden litium som tas och litiumkoncentrationen i blodet inte verkar vara helt proportionella. Detta g\u00e5r lite emot dagens t\u00e4nkande. V\u00e5r modell baserad p\u00e5 dessa f\u00f6ruts\u00e4gelser f\u00f6rklarade runt 50-60 procent av variationen i uts\u00f6ndring av litium. Det \u00e4r b\u00e4ttre \u00e4n tidigare modeller och kan anv\u00e4ndas vid beslut om behandling. Det s\u00e4ger f\u00f6rstef\u00f6rfattaren Vincent Millischer, forskare vid institutionen f\u00f6r molekyl\u00e4r medicin och kirurgi, Karolinska Institutet, och ST-l\u00e4kare vid Medical University of Vienna.<\/p>\n\n\n\n

Studien hittade ocks\u00e5 genetiska samband mellan l\u00e4gre uts\u00f6ndring av litium och ett locus p\u00e5 kromosom 11. Det kunde visa att genetiska varianter som p\u00e5verkar BMI och njurfunktion var f\u00f6rknippade med \u00e4ndrad uts\u00f6ndring av litium. N\u00e4r forskarna adderade de genetiska mark\u00f6rerna till modellen f\u00f6rb\u00e4ttrades dess prediktiva f\u00f6rm\u00e5ga endast marginellt. Forskarna menar dock att fynden \u00f6ppnar f\u00f6r m\u00f6jligheten att i framtiden ytterligare anpassa litiumbehandlingen individuellt f\u00f6r varje individ.<\/p>\n\n\n\n

Digital app f\u00f6r att hj\u00e4lpa psykiatriker<\/h4>\n\n\n\n

\u2013 H\u00e4rn\u00e4st vill vi testa v\u00e5r modell i en klinisk studie f\u00f6r att se om det kan minska tiden det tar att hitta r\u00e4tt m\u00e4ngd litium f\u00f6r varje patient. Om utfallet \u00e4r positivt kommer vi att utveckla en digital app. Den kommer i framtiden att kunna hj\u00e4lpa psykiatriker att identifiera r\u00e4tt litiumdoser f\u00f6r patienter med bipol\u00e4r sjukdom, s\u00e4ger Martin Schalling.<\/p>\n\n\n\n

Forskningen \u00e4r finansierad av Vetenskapsr\u00e5det, Stiftelsen f\u00f6r Strategisk Forskning, Hj\u00e4rnfonden, Stiftelsen S\u00f6derstr\u00f6m K\u00f6nigska, Bror Gadelius Minnesfond, Fonden f\u00f6r Psykisk H\u00e4lsa, Stanley Medical Research Institute, Karolinska Institutet och Karolinska universitetssjukhuset. N\u00e5gra av studief\u00f6rfattarna har erh\u00e5llit ekonomisk ers\u00e4ttning f\u00f6r f\u00f6rel\u00e4sningar och r\u00e5dgivning fr\u00e5n diverse l\u00e4kemedelsbolag.<\/p>\n\n\n\n

Publikation<\/strong>: \u201dImproving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden<\/a>,\u201d Vincent Millischer, Granville J Matheson, Sarah E Bergen, Brandon J Coombes, Katja Ponzer, Fredrik Wikstr\u00f6m, Karolina Jagiello, Martin Lundberg, Peter Stenvinkel, Joanna M Biernacka, Olof Breuer, Lina Martinsson, Mikael Land\u00e9n, Lena Backlund, Catharina Lavebratt, Martin Schalling, The<\/em> Lancet Psychiatry<\/em>, online 13 maj, 2022, doi: 10.1016\/PIIS2215-0366(22)00100-6<\/p>\n\n\n\n


Foto \u00f6verst: Thomas Gustafsson<\/strong><\/p>\n\n\n\n


<\/h3>\n\n\n\n

<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Sex faktorer kan hj\u00e4lpa till att avg\u00f6ra hur mycket litium som beh\u00f6vs f\u00f6r att behandla patienter med bipol\u00e4r sjukdom. Det visar en studie ledd av forskare vid Karolinska Institutet. Studien, […]<\/p>\n","protected":false},"author":6,"featured_media":5203,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4],"tags":[],"acf":[],"yoast_head":"\nSex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom - Bricks staging<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom - Bricks staging\" \/>\n<meta property=\"og:description\" content=\"Sex faktorer kan hj\u00e4lpa till att avg\u00f6ra hur mycket litium som beh\u00f6vs f\u00f6r att behandla patienter med bipol\u00e4r sjukdom. Det visar en studie ledd av forskare vid Karolinska Institutet. Studien, […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\" \/>\n<meta property=\"og:site_name\" content=\"Bricks staging\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/voxvigoruppsala\" \/>\n<meta property=\"article:published_time\" content=\"2022-06-05T00:00:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/voxvigor.se\/bricks-staging\/wp-content\/uploads\/2019\/07\/VV-Lithionit1-TG-Utvald-bild-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"855\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Vox Vigor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Skriven av\" \/>\n\t<meta name=\"twitter:data1\" content=\"Vox Vigor\" \/>\n\t<meta name=\"twitter:label2\" content=\"Ber\u00e4knad l\u00e4stid\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minuter\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\"},\"author\":{\"name\":\"Vox Vigor\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/person\/6317c8a7107854d8acfddb8fafcf0a47\"},\"headline\":\"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom\",\"datePublished\":\"2022-06-05T00:00:06+00:00\",\"dateModified\":\"2022-06-05T00:00:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\"},\"wordCount\":876,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#organization\"},\"articleSection\":[\"Samh\u00e4lle\"],\"inLanguage\":\"sv-SE\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\",\"url\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\",\"name\":\"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom - Bricks staging\",\"isPartOf\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#website\"},\"datePublished\":\"2022-06-05T00:00:06+00:00\",\"dateModified\":\"2022-06-05T00:00:06+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#breadcrumb\"},\"inLanguage\":\"sv-SE\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Start\",\"item\":\"https:\/\/voxvigor.se\/bricks-staging\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u00d6vrigt\",\"item\":\"https:\/\/voxvigor.se\/bricks-staging\/category\/ovrigt\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#website\",\"url\":\"https:\/\/voxvigor.se\/bricks-staging\/\",\"name\":\"Bricks staging\",\"description\":\"En n\u00e4ttidning f\u00f6r dig med psykisk oh\u00e4lsa\",\"publisher\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/voxvigor.se\/bricks-staging\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sv-SE\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#organization\",\"name\":\"Vox Vigor\",\"url\":\"https:\/\/voxvigor.se\/bricks-staging\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sv-SE\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/voxvigor.se\/bricks-staging\/wp-content\/uploads\/2017\/12\/VoxVigorHeader.jpg\",\"contentUrl\":\"https:\/\/voxvigor.se\/bricks-staging\/wp-content\/uploads\/2017\/12\/VoxVigorHeader.jpg\",\"width\":1024,\"height\":254,\"caption\":\"Vox Vigor\"},\"image\":{\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/voxvigoruppsala\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/person\/6317c8a7107854d8acfddb8fafcf0a47\",\"name\":\"Vox Vigor\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sv-SE\",\"@id\":\"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e1e17b70478ec8e963d10e98122b95?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e1e17b70478ec8e963d10e98122b95?s=96&d=mm&r=g\",\"caption\":\"Vox Vigor\"},\"sameAs\":[\"https:\/\/voxvigor.se\/bricks-staging\"],\"url\":\"https:\/\/voxvigor.se\/bricks-staging\/author\/voxvigorgmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom - Bricks staging","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/","og_locale":"sv_SE","og_type":"article","og_title":"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom - Bricks staging","og_description":"Sex faktorer kan hj\u00e4lpa till att avg\u00f6ra hur mycket litium som beh\u00f6vs f\u00f6r att behandla patienter med bipol\u00e4r sjukdom. Det visar en studie ledd av forskare vid Karolinska Institutet. Studien, […]","og_url":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/","og_site_name":"Bricks staging","article_publisher":"https:\/\/www.facebook.com\/voxvigoruppsala","article_published_time":"2022-06-05T00:00:06+00:00","og_image":[{"width":855,"height":450,"url":"https:\/\/voxvigor.se\/bricks-staging\/wp-content\/uploads\/2019\/07\/VV-Lithionit1-TG-Utvald-bild-1.jpg","type":"image\/jpeg"}],"author":"Vox Vigor","twitter_card":"summary_large_image","twitter_misc":{"Skriven av":"Vox Vigor","Ber\u00e4knad l\u00e4stid":"4 minuter"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#article","isPartOf":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/"},"author":{"name":"Vox Vigor","@id":"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/person\/6317c8a7107854d8acfddb8fafcf0a47"},"headline":"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom","datePublished":"2022-06-05T00:00:06+00:00","dateModified":"2022-06-05T00:00:06+00:00","mainEntityOfPage":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/"},"wordCount":876,"commentCount":0,"publisher":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/#organization"},"articleSection":["Samh\u00e4lle"],"inLanguage":"sv-SE","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/","url":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/","name":"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom - Bricks staging","isPartOf":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/#website"},"datePublished":"2022-06-05T00:00:06+00:00","dateModified":"2022-06-05T00:00:06+00:00","breadcrumb":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#breadcrumb"},"inLanguage":"sv-SE","potentialAction":[{"@type":"ReadAction","target":["https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/voxvigor.se\/bricks-staging\/sex-faktorer-for-ratt-litiumdos-for-patienter-med-bipolar-sjukdom\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Start","item":"https:\/\/voxvigor.se\/bricks-staging\/"},{"@type":"ListItem","position":2,"name":"\u00d6vrigt","item":"https:\/\/voxvigor.se\/bricks-staging\/category\/ovrigt\/"},{"@type":"ListItem","position":3,"name":"Sex faktorer f\u00f6r r\u00e4tt litiumdos f\u00f6r patienter med bipol\u00e4r sjukdom"}]},{"@type":"WebSite","@id":"https:\/\/voxvigor.se\/bricks-staging\/#website","url":"https:\/\/voxvigor.se\/bricks-staging\/","name":"Bricks staging","description":"En n\u00e4ttidning f\u00f6r dig med psykisk oh\u00e4lsa","publisher":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/voxvigor.se\/bricks-staging\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sv-SE"},{"@type":"Organization","@id":"https:\/\/voxvigor.se\/bricks-staging\/#organization","name":"Vox Vigor","url":"https:\/\/voxvigor.se\/bricks-staging\/","logo":{"@type":"ImageObject","inLanguage":"sv-SE","@id":"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/logo\/image\/","url":"https:\/\/voxvigor.se\/bricks-staging\/wp-content\/uploads\/2017\/12\/VoxVigorHeader.jpg","contentUrl":"https:\/\/voxvigor.se\/bricks-staging\/wp-content\/uploads\/2017\/12\/VoxVigorHeader.jpg","width":1024,"height":254,"caption":"Vox Vigor"},"image":{"@id":"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/voxvigoruppsala"]},{"@type":"Person","@id":"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/person\/6317c8a7107854d8acfddb8fafcf0a47","name":"Vox Vigor","image":{"@type":"ImageObject","inLanguage":"sv-SE","@id":"https:\/\/voxvigor.se\/bricks-staging\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e1e17b70478ec8e963d10e98122b95?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e1e17b70478ec8e963d10e98122b95?s=96&d=mm&r=g","caption":"Vox Vigor"},"sameAs":["https:\/\/voxvigor.se\/bricks-staging"],"url":"https:\/\/voxvigor.se\/bricks-staging\/author\/voxvigorgmail-com\/"}]}},"_links":{"self":[{"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/posts\/9475"}],"collection":[{"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/comments?post=9475"}],"version-history":[{"count":0,"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/posts\/9475\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/media\/5203"}],"wp:attachment":[{"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/media?parent=9475"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/categories?post=9475"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/voxvigor.se\/bricks-staging\/wp-json\/wp\/v2\/tags?post=9475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}